What question did this study set out to answer?

The aim is to investigate the relationship between apoptosis and left ventricular remodeling following myocardial infarction.

April 30, 20260 citationsOpen Access

Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion

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HWHiroshi Wakabayashi JTJunichi Taki AIAnri Inaki

Key Result

Apoptosis assessed by 99mTc-annexin-V uptake correlates with left ventricular remodeling during the subacute phase of myocardial ischemia and reperfusion in a rat model.

Key Points

The aim is to investigate the relationship between apoptosis and left ventricular remodeling following myocardial infarction.
Utilized a rat model to assess 99mTc-annexin-V uptake.
Analyzed the correlation between apoptosis and left ventricular remodeling after ischemia and reperfusion.
Found a significant correlation between 99mTc-annexin-V uptake and left ventricular remodeling.
Indicated that increased apoptosis is associated with worse remodeling outcomes.

Structured PICO

Population

rat model of myocardial ischemia and reperfusion

Intervention

99mTc-annexin-V (99mTc-AV) uptake assessment

Outcome

Correlation between 99mTc-AV uptake and left ventricular remodeling (LVR)surrogate

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Background: To investigate whether an apoptotic process demonstrated by 99mTc-annexin-V ( 99mTc-AV) uptake correlates with left ventricular remodeling (LVR) after myocardial infarction, we assessed 99mTc-AV uptake in rat model of myocardial ischemia and reperfusion.

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Cite This Study

Wakabayashi et al. (Thu,) reported a other. Apoptosis assessed by 99mTc-annexin-V uptake correlates with left ventricular remodeling during the subacute phase of myocardial ischemia and reperfusion in a rat model.

synapsesocial.com/papers/6a025ea093868c48f3093e2b https://doi.org/https://doi.org/10.24517/00065247