Dihydromyricetin Attenuates Platelet Hyperactivity in HFD/STZ-Induced Diabetic Mice by Inhibiting Intraplatelet ROS Generation

Key Points

• This research aims to explore how dihydromyricetin affects platelet activity and oxidative stress in diabetic mice.
• Used HFD/STZ-induced diabetic mice model to assess the effects of dihydromyricetin
• Measured intraplatelet reactive oxygen species (ROS) levels and platelet activity
• Analyzed cardiovascular risk factors associated with platelet hyperactivity
• Dihydromyricetin treatment significantly reduced intraplatelet ROS generation
• Lowered platelet hyperactivity was observed post-treatment, leading to reduced cardiovascular complications