dual-nanopore device and achieved a substantial further increase in the cocaptured translocation time. Molecular dynamics simulations elucidate the underlying mechanism: the graphene layer modulates the axial potential inside the nanopore, inducing a more gradual drop and consequently attenuating the effective electric field gradient in the cocapture region. Concurrently, strong van der Waals and π-π interactions between the graphene surface and DNA significantly enhance interfacial adhesion. The combination of geometric tug-of-war and interfacial adsorption effects synergistically decelerates the cocaptured DNA translocation. These findings enable fine-tuned control over DNA translocation dynamics without sacrificing the signal-to-noise ratio, laying a foundation for constructing next-generation solid-state nanopore platforms with high resolution and high fidelity.
Si et al. (Tue,) studied this question.