In silico analysis of interactions between histo-blood group antigen–associated glycans and VP1 proteins of human and animal noroviruses

Key Points

• The analysis aims to investigate how histo-blood group antigen-associated glycans interact with VP1 proteins of noroviruses.
• In silico analysis performed to examine protein-glycan interactions.
• Comparison between human and animal norovirus VP1 proteins conducted.
• Identified specific binding patterns of glycans to VP1 proteins.
• Demonstrated potential implications for norovirus transmission and vaccine development.