BACKGROUND: Chemotherapy-induced nausea and vomiting, together with depression and anxiety, are common and distressing complications in patients with colorectal cancer that seriously impair quality of life and treatment adherence. This study explored the efficacy of mindfulness-based stress reduction (MBSR) in relieving chemotherapy-related physical and psychological distress. METHODS: This retrospective cohort study included 301 patients with colorectal cancer undergoing chemotherapy. The control group received routine nursing care, whereas the MBSR group completed an 8-week intervention including mindful breathing, body scan, and meditation. FLIE, PHQ 9 and GAD 7 were used to assess symptoms over four chemotherapy cycles. RESULTS: < 0.001). The MBSR group exhibited a clear ameliorative trend with both baseline and post-intervention scores declining throughout the treatment course, confirming its efficacy in alleviating depressive and anxiety symptoms. CONCLUSION: MBSR effectively relieves chemotherapy-induced nausea, vomiting, depression, and anxiety, and is worthy of clinical application to improve the physical and psychological status and quality of life of patients with colorectal cancer.
黄敏清 et al. (Wed,) studied this question.