accelerating hepatic regeneration in acute liver failure (ALF). Their preclinical studies demonstrate 37 improved survival, enhanced hepatocyte proliferation via activation of MAPK cell 38 signalling pathways, and reduced inflammatory gene expression. These findings not only expand the of beyond their traditional hemostatic roles but also that 40 modulation of endogenous regenerative pathways may offer viable alternatives to liver 41 transplantation, which remains severely limited by donor availability and substantial cost.
Turcu-Ştiolică et al. (Tue,) studied this question.