)-one, and amides containing an active methylene group to efficiently assemble structurally unique α-pyrone aromatic lactones. Notably, this work achieves the direct transformation of amides into aromatic lactones within a multicomponent framework, overcoming the traditional limitation of forming only linear esters, and establishes a new platform for inert amide functionalization and complex heterocycle synthesis.
Ma et al. (Thu,) studied this question.