Biocompatible and structurally stable near-spherical PLNP@PDA@PW 12 nanoplatforms for precise temperature sensing and photothermal therapy

Key Points

• This research aims to develop biocompatible nanoplatforms for precise temperature sensing and effective photothermal therapy.
• Synthesis of near-spherical core-shell PLNP@PDA nanoplatforms
• Covalent conjugation of persistent luminescent nanoparticles with polydopamine
• Characterization of nanoplatforms' structural stability and biocompatibility
• Nanoplatforms achieved an average diameter of 58.6 nm
• Demonstrated effective photothermal conversion capabilities
• Showed high biocompatibility in preliminary assessments