The vital role of testosterone in normal female physiology and wellbeing is largely ignored by researchers and healthcare providers. The lack of recognition of the importance of testosterone in female health creates a health disparity. Androgens are the most abundant sex hormone in all humans, including females. However, the traditional view that testosterone is a male hormone and estrogen is a female hormone is not supported by scientific evidence. Emerging research shows that testosterone plays a crucial role in female reproduction, cardiovascular health, bone remodeling, muscle mass, and brain function. This article aims to review the literature on the physiological role of testosterone in females, the challenges in measuring testosterone levels, and the implications for female health. The authors conducted a review of the literature on testosterone in female physiology, including its biosynthesis, measurement, and effects on various bodily functions. There is a significant gap in research and understanding of the role of testosterone in female health. Barriers to recognizing the importance of testosterone include a male-centric medical system, the lack of standard reference ranges for testosterone during the menstrual cycle, and the general lack of understanding of endogenous testosterone in female endocrinology. There is a clear need for further research and clinical trials to address this health disparity.
Faucett et al. (Fri,) studied this question.