Itraconazole as a repurposed anti-cancer agent: focusing on synthesis, mechanisms of action and therapeutic insights

Key Points

• This research aims to explore itraconazole as a repurposed anti-cancer drug, assessing its mechanisms and therapeutic potential.
• Conducted a thorough literature review on itraconazole's synthesis and anti-cancer mechanisms.
• Analyzed the existing preclinical and clinical data regarding its therapeutic insights.
• Itraconazole shows promise in inhibiting tumor growth through multiple mechanisms of action.
• Demonstrated effectiveness in various cancer types, warranting further investigation in clinical settings.