Photodegradable Hydrogels In the Research Article (e09246), Jacopo Di Russo and co-workers present a light-tunable hydrogel platform that enables precise spatial control of extracellular matrix topography. By combining micro engineered substrates with defined mechanical and biochemical cues, the system recreates dynamic microenvironmental changes that stress the retinal pigment epithelium. This platform enables systematic investigation of mechanobiological responses associated with age-related outer retinal pathologies.
Reul et al. (Fri,) studied this question.