Molecular networking-assisted isolation, structural elucidation, and bioactivity evaluation of new diterpenoids from Chaetocarpus castanocarpus

Key Points

• The aim is to isolate and evaluate the bioactivity of new diterpenoids derived from Chaetocarpus castanocarpus.
• Used molecular networking for the isolation of new diterpenoids.
• Conducted structural elucidation of compounds to understand their features.
• Evaluated the bioactivity of the isolated diterpenoids.
• Several new diterpenoids were successfully isolated and structurally elucidated.
• The bioactivity assessment indicated these compounds show potential as drug leads.