Elevated pulmonary arterial pressure independently predicted all-cause death or unplanned rehospitalisation within 90 days in older adults with heart failure (adjusted HR 2.56; 95% CI 1.10-5.98).
Cohort (n=156)
No
What are the cardiogeriatric and cardiopulmonary predictors of early adverse outcomes in older adults hospitalized for heart failure?
In older adults hospitalized for heart failure, early post-discharge outcomes are primarily driven by haemodynamic factors such as elevated pulmonary arterial pressure rather than frailty severity alone.
Effect estimate: HR 2.56 (95% CI 1.10-5.98)
BACKGROUND 51% women), 43 patients (27.6%) experienced an adverse event within 90 days, including 11 deaths (7.1%) and 32 unplanned rehospitalisations (20.5%). Cox regression analyses were performed for 124 patients with complete data. Elevated pulmonary arterial pressure emerged as an independent predictor of adverse outcomes (adjusted hazard ratio 2.56, 95% confidence interval 1.10-5.98). In contrast, left ventricular ejection fraction and classical geriatric markers were not associated with early events. A preserved metabolic profile was associated with lower rehospitalisation rates. Frailty-related variables were not independently associated with early outcomes. CONCLUSIONS: In older adults hospitalised for HF, early post-discharge outcomes appear driven primarily by haemodynamic and cardiopulmonary factors rather than frailty severity alone. These findings support a cardiogeriatric model integrating haemodynamic assessment, frailty-aware follow-up and structured post-discharge monitoring to improve early outcomes in ageing HF populations.
Maurou et al. (Fri,) conducted a cohort in heart failure (n=156). Elevated pulmonary arterial pressure was evaluated on all-cause death or unplanned rehospitalisation within 90 days after hospital discharge (HR 2.56, 95% CI 1.10-5.98). Elevated pulmonary arterial pressure independently predicted all-cause death or unplanned rehospitalisation within 90 days in older adults with heart failure (adjusted HR 2.56; 95% CI 1.10-5.98).