February 21, 2026Open Access

Identification of quinolinyl-containing dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors with moderate potency towards acetylcholinesterase

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Abstract

revealed key interactions with FAAH and sEH but limited interactions with AChE, suggesting directions for future structural modifications that could improve potency and selectivity.

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Gonzalez et al. (Sat,) studied this question.

synapsesocial.com/papers/6a09df03b0d552aa8b45ed1d https://doi.org/https://doi.org/10.1016/j.rechem.2026.103159

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