Abstract Objective To investigate the trends in mortality and disease burden of lower respiratory infections (LRI) among Chinese residents from 2008 to 2021. Methods Based on the Chinese Cause of Death Surveillance Dataset, indicators such as the crude mortality rate (CMR), age-standardized mortality rate (AMSR), potential years of life lost (PYLL), and potential years of life lost rate (PYLLR) of LRI among Chinese residents from 2008 to 2021 were analyzed by gender, age, urbanrural division, and region. Joinpoint regression analysis was conducted for AMSR and PYLLR, and an Age-Period-Cohort model analysis was performed for AMSR. Results From 2008 to 2021, the AMSR of LRI was higher in males than in females (except in 2009), higher in urban areas than in rural areas, and higher in the western region than in the eastern and central regions. The PYLLR of LRI was higher in males than in females, higher in rural areas than in urban areas, and higher in the western region than in the central and eastern regions. Both AMSR and PYLLR showed an overall declining trend. Additionally, LRI-related deaths primarily occurred among infants and the elderly. Conclusion Although the mortality and disease burden of LRI in China have declined rapidly, primary prevention should still be emphasized for infants, the elderly, males, rural residents, and those in the western region. This abstract is funded by: China National Natural Science Foundation
Yu et al. (Fri,) studied this question.