Between 1999 and 2023, the overall age-adjusted mortality rate for co-occurring cardiac and pulmonary arrest declined non-significantly from 3.89 to 3.66 per 100,000 (AAPC -0.06; p=0.908).
Observational (n=191,576)
Yes
Cardiopulmonary arrest mortality in the US showed a modest overall decline from 1999 to 2023 but spiked between 2015 and 2021, with persistent disparities affecting Black individuals, men, and rural populations.
Effect estimate: AAPC -0.06 (95% CI -1.22 to 1.10)
Absolute Event Rate: 3.66% vs 3.89%
p-value: p=0.908
Abstract Introduction Cardiac and pulmonary arrest are critical public health challenges, representing acute medical emergencies with high fatality rates when not treated promptly. The study helps in identifying areas that need improvement in prevention and emergency response. Methods Using the CDC WONDER multiple cause of death files for adults aged ≥25, we analyzed age-adjusted mortality rates (AAMRs) per 100,000 for respiratory arrest (ICD-10 codes: RO9.2) and cardiac arrest (ICD-10 codes: I46), stratified by year, gender, race/ethnicity, and geography. Joinpoint regression was used to estimate average annual percent change (AAPC) and annual percent change (APC) with 95% confidence intervals (CIs). Statistical significance was defined as p 0.05. Results From 1999 to 2023, 191,576 deaths were reported where cardiac and pulmonary arrest co-occurred, mostly in medical facility inpatients. The overall AAMR declined from 3.89 in 1999 to 3.66 in 2023 (AAPC: -0.06; 95% CI: -1.22 to 1.10; p = 0.908), with a pronounced increase between 2015 and 2021 (APC: 11.56; p 0.001). Adults aged ≥65 recorded the highest overall AAMR at 13.61. Both genders exhibited an upward trend in AAMRs before declining after 2021, with men having higher AAMRs than women (3.92 vs 3.00). By race, AAMRs were greatest in Non-Hispanic (NH) Black or African American (5.04) and lowest in NH Asian or Pacific Islanders (2.31). Rural areas (3.96) exceeded urban areas (3.15). Regionally, the South recorded the peak AAMR at 4.00. At the state level, the top 90th percentile included Alabama, California, Connecticut, and Oklahoma. Conclusion Combined mortality from cardiac and pulmonary arrest has declined modestly over the past two decades, disproportionately affecting Black or African American individuals, the population of the South and nonmetropolitan areas, and certain central states. Continued efforts are needed to address disparities, improve emergency response, and support early intervention, especially in high-risk groups. This abstract is funded by: No funding
Shalabi et al. (Fri,) conducted a observational in Cardiac and pulmonary arrest (n=191,576). Between 1999 and 2023, the overall age-adjusted mortality rate for co-occurring cardiac and pulmonary arrest declined non-significantly from 3.89 to 3.66 per 100,000 (AAPC -0.06; p=0.908).