What question did this study set out to answer?

The aim is to evaluate the diagnosis and clinical management of tuberculosis associated with HIV in adults.

May 21, 2026

HIV-Associated Tuberculosis in Adults: Diagnosis and Clinical Management

GMGraeme MeintjesUniversity of Cape Town BSBianca SossenUniversity of Cape Town

Key Points

The aim is to evaluate the diagnosis and clinical management of tuberculosis associated with HIV in adults.
Management strategies for rifampicin-resistant tuberculosis were explored.
Focus on a 6-month oral regimen for treatment.
Identification of ongoing challenges in HIV-associated TB management.
Recent efforts have reduced mortality rates in HIV-associated TB.
Ongoing challenges remain in effective management.
Active clinical trials are addressing these issues.

Abstract

) and is currently not widely available. Management of rifampicin-resistant TB now involves a 6month all-oral regimen for most patients, including PWH. While significant gains have recently been made toward decreasing mortality from HIV-associated TB, there are many ongoing challenges, some of which are being addressed in active clinical trials.

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