What question did this study set out to answer?

This research aims to evaluate how Mongolian Andai therapy affects gut microbiota and metabolic profiles in patients with depression.

May 21, 2026Open Access

Therapeutic impact of Mongolian Andai therapy on gut microbiota and metabolomic profiles in depression

Key Points

This research aims to evaluate how Mongolian Andai therapy affects gut microbiota and metabolic profiles in patients with depression.
Twenty patients received 8 weeks of Andai therapy.
Fecal samples were analyzed using 16S rRNA sequencing to assess gut microbiota changes.
Blood metabolomics were performed alongside evaluating treatment response using HAMD scores.
Andai therapy significantly altered gut microbiota composition in improved patients.
Metabolic profiles showed marked changes correlating with treatment response.
HAMD scores indicated significant improvement in depression symptoms among participants.

Abstract

This study investigated the therapeutic effects of Mongolian Andai therapy in patients with depression by integrating fecal 16S rRNA sequencing and blood metabolomics. Twenty patients received 8 weeks of Andai therapy, and treatment response was evaluated using HAMD scores. The results showed that Andai therapy was associated with significant changes in gut microbiota composition and metabolic profiles, especially in improved patients.

Therapeutic impact of Mongolian Andai therapy on gut microbiota and metabolomic profiles in depression

Key Points

Abstract

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