CD4+ T cells in Type 1 Diabetes: Inferring Stage-specific Dysregulation from scRNA-seq

Key Points

• The aim is to understand how CD4+ T cells are dysregulated at different stages of Type 1 Diabetes using single-cell RNA sequencing.
• Utilized single-cell RNA-seq data processing and analysis.
• Accessed raw .fastq files from the European Nucleotide Archive.
• Included comprehensive README documentation for data details.
• Identified stage-specific patterns of dysregulation in CD4+ T cells associated with Type 1 Diabetes.
• Provided insights into immune responses at various stages of the disease.