Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic neoplasm of the head and neck,1 characterized by a benign epithelial component and a malignant mesenchymal component that exhibits sarcomatous features. While AFS is histologically similar to ameloblastic fibroma, its ectomesenchymal component demonstrates marked cellularity and pleomorphism. A systematic review reported that AFS typically affects younger patients, with a mean age of 27.7 ± 15.6 years, and primarily occurs in the mandible.
Musha et al. (Fri,) studied this question.