Electrospun Zn-cobimetinib-levofloxacin-PVA/PVP nanofibers for skin-targeted anticancer and antimicrobial applications | Synapse
May 28, 2026Open Access
Electrospun Zn-cobimetinib-levofloxacin-PVA/PVP nanofibers for skin-targeted anticancer and antimicrobial applications
Key Points
This research investigates the effectiveness of electrospun Zn-coordinated nanofibers in treating skin cancer and infections.
Utilized electrospinning to create Zn-coordinated PVA/PVP nanofibers.
Assessed simultaneous effects on skin cancer cells and microbial pathogens.
Evaluated the multifunctional potential for therapeutic wound dressings.
Zn-coordinated nanofibers significantly suppressed skin cancer cells and microbial pathogens.
Demonstrated dual therapeutic effects for both anticancer and antimicrobial applications.
Abstract
Electrospun Zn-coordinated PVA/PVP nanofibers simultaneously suppress skin cancer cells and microbial pathogens (bacterial and fungi), providing a multifunctional platform for therapeutic wound dressings.