Turning an Intrinsically Inefficient Reaction Efficient: Homogeneously Catalyzed Continuous-Flow Amination of Alcohols with Ammonia

Key Points

• The aim is to enhance the synthesis efficiency of primary amines from alcohols and ammonia using continuous-flow methods.
• Used a continuous-flow setup for amination reactions.
• Employed homogeneous catalysis for improved efficiency.
• Monitored the reaction conditions and yields.
• Achieved a significant increase in amine yields compared to traditional methods.
• Reaction efficiency was notably enhanced, reducing waste generation.
• Demonstrated application potential in pharmaceuticals and agrochemicals.