Background: Urinary tract infections (UTIs) are among the most common infections encountered in both outpatient and inpatient settings. This study aimed to determine the prevalence of UTIs, identify the causative uropathogens, and characterise their antimicrobial resistance profiles in a secondary care hospital in Mumbai suburban. Methods: A retrospective study was conducted from May 2025 to April 2026 at a secondary care hospital in Mumbai suburban. A total of 992 urine samples were collected from OPD/IPD patients using the midstream clean-catch technique and processed using standard microbiological methods. Antimicrobial susceptibility testing was performed by the Kirby-Bauer disc diffusion method on Mueller-Hinton agar. Results: Of 992 samples, 142 (14.31%) yielded significant pathogen growth. Gram-negative organisms predominated. Escherichia coli was the most common isolate (71/142, 50.00%), followed by Klebsiella pneumoniae (28/142, 19.71%), Pseudomonas aeruginosa (9/142, 6.33%), Enterobacter spp. (7/142, 4.92%), Citrobacter spp. (4/142, 2.81%), Acinetobacter spp. (5/142, 3.52%), Proteus spp. (4/142, 2.81%), Staphylococcus spp. (4/142, 2.81%), Candida spp. (5/142, 3.52%), Enterococcus spp. (3/142, 2.11%), and Providencia stuartii (1/142, 0.70%). The 21–40 age group was most affected, with females comprising the majority. E. coli showed high resistance to ciprofloxacin (61.97%), ampicillin (53.52%), and co-trimoxazole (32.39%), with better susceptibility to imipenem and meropenem. Conclusions: Gram-negative organisms, predominantly E. coli, remain the leading cause of UTIs. Rising resistance to fluoroquinolones and beta-lactams necessitates culture-guided therapy. Regular antibiogram surveillance is essential for effective clinical management.
Babasaheb Tukaram Khade (Thu,) studied this question.