Neurodevelopment arises from the complex interplay of genetic, epigenetic, neurobiological, environmental, and experiential factors that shape the maturation of brain and adaptive functions. Early experiences, particularly within sensitive developmental periods, can either support or disrupt these processes, influencing vulnerability to neurodevelopmental disorders. Among early environmental determinants, family represents the most proximal and dynamic context for the developing child, providing the primary sources of stimulation, emotional regulation, and caregiving. The family environment encompasses both structural (e.g., socioeconomic conditions) and relational (e.g., parent–child interactions, parental mental health) dimensions that jointly influence neurodevelopmental trajectories. This narrative review examines how key domains of the family environment serve as protective factors or sources of vulnerability through their mutual interplay in shaping child neurodevelopment, with the aim of synthesizing current evidence and highlighting directions for early preventive and therapeutic interventions.
Loi et al. (Fri,) studied this question.