Engineered Bacterial Nanosyringes Induce Transient and Controllable Hepatic Immune-Metabolic Responses

Key Points

• To explore how engineered bacterial nanosyringes can induce controlled immune and metabolic responses in the liver.
• Utilized genetically engineered bacteria to create nanosyringes.
• Evaluated the temporal and controllable responses in hepatic tissues.
• Analyzed immune and metabolic markers post-exposure.
• Engineered nanosyringes induced significant alterations in hepatic immune response (p<0.01).
• Transient metabolic changes were observed, showing a peak response at 4 hours (p<0.05).
• No adverse effects on liver function were reported.