Asthma is a chronic inflammatory respiratory disorder characterized by airway hyperresponsiveness, bronchoconstriction, and mucus overproduction. Despite the availability of various pharmacological treatments, effective disease management remains a challenge due to poor patient compliance, frequent dosing requirements, and limitations of conventional dosage forms. Novel drug delivery systems have emerged as promising strategies to enhance therapeutic efficacy and improve patient adherence. Among these, bilayer drug delivery systems have gained considerable attention due to their ability to provide immediate as well as sustained drug release in a single dosage form. This review highlights the design, formulation strategies, and therapeutic evaluation of bilayer drug delivery systems for asthma management. It discusses the pathophysiology of asthma, limitations of current therapies, advantages of bilayer systems, formulation approaches, evaluation techniques, and future perspectives. The integration of advanced drug delivery technologies is emphasized to achieve improved therapeutic outcomes in asthma treatment.
Manju et al. (Fri,) studied this question.