A-D-A structured phototheranostics for NIR fluorescence imaging guided Type I/II photodynamic and photothermal therapy of tumor

Key Points

• The aim is to develop a single-component nanotheranostic platform for enhanced tumor imaging and therapy.
• Utilized 4TIC nanoparticles formed through molecular self-assembly.
• Applied single-wavelength (808 nm) laser irradiation for therapy.
• Conducted experiments to evaluate the effectiveness of fluorescence imaging and phototherapy.
• 4TIC nanoparticles effectively improved tumor targeting and imaging.
• Significantly enhanced therapeutic effects observed in treated groups compared to controls.
• NIR fluorescence imaging allowed precise monitoring of treatment response.