Imbalanced neurogenesis and gliogenesis in the developing neocortex of mice lacking the proteoglycan Tsukushi

Key Points

• The aim is to investigate how the absence of Tsukushi affects neurogenesis and gliogenesis in the developing neocortex of mice.
• Assessing cortical development in mice lacking Tsukushi.
• Analyzing neurogenesis and gliogenesis processes.
• Investigating potential links to hydrocephalus.
• Neurogenesis and gliogenesis are significantly imbalanced in Tsukushi-deficient mice.
• Alterations in these processes are observed during neocortical development.
• Potential contributions to hydrocephalus were indicated.