ABSTRACT Early diagnosis and disease progression management for chronic conditions create an urgent demand for continuous multidimensional physiological monitoring technologies. Flexible pressure sensors, with their structural flexibility, high sensitivity, low power consumption, and excellent biocompatibility, have emerged as a core potential candidate in the field of healthcare monitoring. This paper systematically reviews the research progress and application prospects of flexible pressure sensors in medical applications. First, the core working principles and performance characteristics of four pressure sensors (piezoresistive, piezocapacitive, triboelectric, and piezoelectric sensors) are introduced. Second, we discuss key strategies for enhancing sensor performance across four dimensions, including material systems, device architecture, mechanism modeling, and intelligent algorithms. Subsequently, cutting‐edge applications across five medical scenarios, including cardiovascular diseases, respiratory disorders, laryngeal and speech impairments, brain diseases, and eye diseases, are presented and discussed. Finally, current challenges hindering the clinical application of flexible pressure sensors and future development directions of flexible pressure sensors in medical application are analyzed.
Su et al. (Sat,) studied this question.