Chronic urticaria is considered one of the most common dermatological and allergic diseases characterized by recurrent skin rashes, itching, and angioedema. Traditional antihistamine therapy is not always effective, especially in autoimmune and resistant forms of the disease. Plasmapheresis is a modern extracorporeal detoxification method that allows the removal of circulating immune complexes, autoantibodies, inflammatory mediators, and toxic substances from the blood plasma. This article discusses the role of plasmapheresis in the complex treatment of chronic urticaria, its pathogenetic mechanisms, clinical efficacy, and prospects in dermatological practice. The analysis demonstrates that plasmapheresis significantly improves the clinical condition of patients and reduces the frequency of relapses when combined with standard therapy.
Saxob Alijonovich Azimov (Mon,) studied this question.