Key points are not available for this paper at this time.
• The terminology around formation of protein aggregates and supramolecular structures is defined. • Protein assemblies are heterogeneous in size and in other physiochemical properties. • NMR spectroscopy is pivotal to protein self-assembly studies. • Main NMR parameters reporting on protein assembly are signal intensity and linewidth, relaxation rates, diffusion coefficient, chemical shifts and chemical exchange. • NMR approaches are gaining recognition for in-line and quality control of bioprocesses.
Zalar et al. (Fri,) studied this question.