Regiodivergent Synthesis of gem -Difluoroalkenes Enabled by Electron Donor–Acceptor Complex-Mediated C–F Bond Photoreduction of α-Trifluoromethylstyrenes | Synapse
June 4, 2026
Regiodivergent Synthesis of gem -Difluoroalkenes Enabled by Electron Donor–Acceptor Complex-Mediated C–F Bond Photoreduction of α-Trifluoromethylstyrenes
Key Points
The aim is to achieve regiodivergent synthesis of gem-difluoroalkenes using electron donor-acceptor complex-mediated reactions.
Utilized electron donor-acceptor complexes for C-F bond photoreduction.
Focused on α-trifluoromethylstyrenes as substrates.
Successfully produced various gem-difluoroalkenes with tailored regioselectivity through photoreduction.
Demonstrated the feasibility of manipulating C-F bonds under mild conditions.