Dual role of homocysteine in enhancing metabolic activity and suppressing inflammatory cytokines in murine immune cells

Key Points

• The study investigates the dual effects of homocysteine on immune cells, focusing on its role in modulation and inflammation.
• Examined effects of homocysteine on murine immune cells
• Assessed changes in macrophage phenotype and cytokine levels
• Utilized stress-mediated regulatory mechanisms
• Homocysteine promoted improved macrophage maturation and recruitment of antigen-presenting cells.
• Reduced excessive release of inflammatory cytokines through regulatory mechanisms.