Thianthrenation-enabled metal-free heterodifunctionalization of unactivated alkenes with thiols and readily available N/O nucleophiles

Key Points

• To develop a simple and green method for the 1,2-heterodifunctionalization of unactivated alkenes using thiols and nucleophiles.
• Thianthrenation as a strategy for activating unactivated alkenes.
• Utilization of thiols and readily available N/O nucleophiles in the transformation process.
• No metal catalysts are involved, enhancing the green aspect of the method.
• Successfully achieved heterodifunctionalization of alkenes with high efficiency.
• Demonstrated compatibility with various nucleophiles, broadening the scope of the method.
• Yielded valuable compounds with minimal environmental impact.