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Retrospective chart review on psychiatric manifestations of GLP-1 agonist usage | Synapse
March 3, 2026
Retrospective chart review on psychiatric manifestations of GLP-1 agonist usage
BS
Brianna Sa
University of Miami
AM
Anthony Maristany
University of Miami
AS
Ashwin Subramaniam
University of Miami
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Key Points
Psychiatric manifestations linked to GLP-1 agonists include anxiety and depression, showing a clear impact on mental health.
Review of patient charts revealed significant psychiatric symptoms in 30% of those on GLP-1 agonists.
Retrospective chart review across multiple clinics identified various medication effects on mental health and neurobiology.
Findings support the need for further study on the psychiatric implications of GLP-1 agonist treatments.
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Sa et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75bbac6e9836116a23977
https://doi.org/https://doi.org/10.1016/j.jpsychires.2026.01.042