Positive association between serum uric acid and metabolic dysfunction-associated steatotic liver disease: insights from a Japanese health checkup cohort | Synapse
March 3, 2026Open Access
Positive association between serum uric acid and metabolic dysfunction-associated steatotic liver disease: insights from a Japanese health checkup cohort
Key Points
Metabolic dysfunction-associated steatotic liver disease is positively associated with serum uric acid levels, indicating higher risk.
Each 1 mg/dL increase in serum uric acid was linked to a 1.5-fold increase in metabolic dysfunction-associated steatotic liver disease.
Cohort analysis included data from health checkups of Japanese adults, assessing serum uric acid and metabolic parameters.
Highlighting the need for further exploration of how serum uric acid could influence liver health and metabolic function.