March 3, 2026Open Access

Expert recommendations for setting and adjusting airway pressure release ventilation based on clinical experience and basic science evidence

Key Points

Optimizing airway pressure release ventilation settings improves patient outcomes with acute lung injury and ARDS.
The panel developed recommendations based on solid clinical evidence and expert experiences from diverse healthcare settings.
Assessment of lung-protective settings in APRV mode is crucial for managing patients with increased elastance disorders.
Expert recommendations may enable better personalized adjustments in APRV, enhancing respiratory support effectiveness.

Abstract

The panel developed a protocol for adjusting the four APRV settings based on expert experience and solid clinical and scientific evidence for patients with ALI and ARDS, or disorders of normal or increased elastance. Optimizing the lung-protective settings in APRV mode can improve patient outcomes.

Expert recommendations for setting and adjusting airway pressure release ventilation based on clinical experience and basic science evidence

Key Points

Abstract

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