Revealing the Mechanism of Chang-Shuang-Li-Zhong Powder in theTreatment of Ulcerative Colitis based on Network PharmacologyApproach

Key Points

• The aim is to elucidate how Chang-Shuang-Li-Zhong Powder works in treating ulcerative colitis.
• Utilized a network pharmacology approach to analyze the effects of CSLZ.
• Examined the impact on colitis-related inflammatory pathways.
• Investigated the inhibition of PI3K/Akt and MAPK pathways.
• CSLZ significantly alleviates inflammation associated with colitis.
• Inhibition of PI3K/Akt and MAPK pathways was demonstrated as a key mechanism.

Abstract