Persistent Elevation of β-hCG Levels in a Patient with Primary Malignant Giant Cell Tumor of Bone: a Case Report and Literature Review

Key Points

• To explore the connection between malignant giant cell tumor of bone and elevated β-hCG levels.
• Case report documenting β-hCG levels in a patient with MGCTB.
• Literature review to identify similar cases and outcomes.
• Analysis of diagnostic considerations for ectopic hormone secretion.
• Observed persistent elevation of β-hCG in the patient.
• Identified MGCTB as a potential, unrecognized source of ectopic β-hCG secretion.
• Suggested need for clinicians to consider MGCTB in differential diagnoses for elevated β-hCG.

Abstract