Evaluation of tissue perfusion in septic shock using cardiac output monitoring and transcutaneous oxygen challenge test: A prospective observational study

Key Points

• The study aims to evaluate tissue perfusion in septic shock using various monitoring techniques and their prognostic implications.
• Conducted a prospective observational study on septic shock patients.
• Utilized the 10min-OCT as a non-invasive marker for microcirculatory perfusion.
• Monitored cardiac output and assessed lactate levels to determine circulatory status.
• 10min-OCT correlated with lactate levels indicating reliable perfusion assessment.
• VTI was found to be more sensitive than cardiac output or cardiac index.
• CaO₂ and CvO₂ identified as independent predictors of 28-day mortality.