Early Immune Phenotype–Guided Immunomodulatory Strategies and Intensive Care Outcomes in Septic Shock: A Single-Center Retrospective Cohort Study

Key Points

• This study investigates the effects of early immune phenotype-guided immunomodulatory strategies on outcomes for patients with septic shock.
• Single-center retrospective cohort design
• Included patients with septic shock surviving beyond 24 hours
• Analyzed patterns of hemodynamic stabilization and organ recovery
• Immunomodulatory strategies were associated with distinct patterns of hemodynamic stabilization
• There was notable organ recovery in patients receiving targeted interventions
• Findings suggest potential for improved clinical outcomes, warranting further investigation

Abstract