A Physics-Guided Machine Learning Algorithm for Non-Ionizing Femur Fracture Classification from RF Spectral Data

This paper presents a physics-guided machine learning algorithm for classifying femur fracture presence and subtype using non-ionising radiofrequency (RF) spectral data. Multi-sensor S-parameter responses were generated from a femur phantom model across 1.0–3.0 GHz, producing 104 specimens representing intact bone and three fracture geometries. An exploratory, effect-size-driven band-selection algorithm identified a compact discriminative region between 1.74 and 1.90 GHz. Interpretable classifiers, including k-nearest neighbours (KNN), decision trees, linear discriminant analysis, and Naïve Bayes, were evaluated under strict specimen-level hold-out protocols to prevent data leakage. The KNN algorithm achieved 99.3% frame-level accuracy and 100% specimen-level accuracy for binary fracture detection while maintaining strong robustness in multiclass subtype classification, validated through sensor ablation and leave-one-subtype-out testing. The results demonstrate that compact, interpretable algorithms operating on band-limited RF spectra can achieve reliable, radiation-free fracture classification, supporting future development of continuous and edge-deployable monitoring systems.