Where do we stand now regarding protein nanoparticles? perspectives from the six thinking hats framework

Key Points

• To examine the challenges and potential solutions in the field of protein nanoparticles (PNPs) using the Six Thinking Hats framework.
• Applied the Six Thinking Hats framework to review protein nanoparticles.
• Identified key bottlenecks like stability, production, and targeting.
• Discussed applicability to other nanodelivery systems.
• Highlighted the core issues in PNPs, particularly stability, production, and targeting.
• Demonstrated the framework's potential to guide clinical translation of PNPs.
• Proposed interdisciplinary approaches to foster innovation in nanodelivery.

Abstract