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April 15, 2026Open Access

Peptoid-based antimicrobial strategies against polymyxin-resistant Gram-negative bacteria

Key Points

The aim is to evaluate TM8 as a potential antimicrobial candidate targeting polymyxin-resistant bacteria.
Evaluation of antimicrobial efficacy of TM8 against polymyxin-resistant bacteria.
Recommendations for further studies on safety and pharmacokinetics of TM8.
TM8 shows promise as an antimicrobial agent against resistant strains.
Further studies are needed to assess safety profiles and detailed pharmacological properties.

Abstract

This study presents TM8 as a potential candidate antimicrobial against polymyxin-resistant bacteria. Further studies are recommended focusing on safety, pharmacokinetics and pharmacodynamics of this compound.

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Peptoid-based antimicrobial strategies against polymyxin-resistant Gram-negative bacteria | Synapse

Cite This Study

Mishra et al. (Wed,) studied this question.

synapsesocial.com/papers/69df2b85e4eeef8a2a6b0880 https://doi.org/https://doi.org/10.1093/jambio/lxag093