补充图15：SPP1+肿瘤相关巨噬细胞通过CD8+ T细胞功能障碍驱动透明细胞肾细胞癌的免疫治疗耐药

Jiang 等人（周三）研究了该问题。

www.synapsesocial.com/papers/68de68f183cbc991d0a21aed — DOI: https://doi.org/10.1158/2326-6066.30255436

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. Supplementary Figure 14 from SPP1<sup>+</sup> Tumor-Associated Macrophages Drive Immunotherapy Resistance via CD8<sup>+</sup> T-cell Dysfunction in Clear-Cell Renal Cell Carcinoma· 2025
2. Supplementary Figure 13 from SPP1<sup>+</sup> Tumor-Associated Macrophages Drive Immunotherapy Resistance via CD8<sup>+</sup> T-cell Dysfunction in Clear-Cell Renal Cell Carcinoma· 2025
3. Supplementary Figure 1 from SPP1<sup>+</sup> Tumor-Associated Macrophages Drive Immunotherapy Resistance via CD8<sup>+</sup> T-cell Dysfunction in Clear-Cell Renal Cell Carcinoma· 2025
4. Supplementary Figure 12 from SPP1<sup>+</sup> Tumor-Associated Macrophages Drive Immunotherapy Resistance via CD8<sup>+</sup> T-cell Dysfunction in Clear-Cell Renal Cell Carcinoma· 2025
5. Supplementary Figure 19 from SPP1<sup>+</sup> Tumor-Associated Macrophages Drive Immunotherapy Resistance via CD8<sup>+</sup> T-cell Dysfunction in Clear-Cell Renal Cell Carcinoma· 2025