THE UNIVERSAL COHERENCE PRINCIPLE: From Atomic Nuclei to Galactic Cores, and Its Implications for Human Disease

English This Manifesto presents a groundbreaking theoretical proposal in Biophysics and Systems Engineering, introducing the Universal Coherence Principle based on the LAW OF EXISTENCE. The work formalizes the dimensioning of Axial Torque through the Axial Coherence Factor (ACF), demonstrating a consistent mathematical pattern (ACF = 0. 65 0. 02) that governs stability across 36 orders of magnitude—from atomic nuclei (10^-15m) to galactic cores (10^21m). The author challenges current biological and physical paradigms by proposing that human diseases, including cancer and neurodegenerative disorders, are manifestations of "Axial Decoherence"—a loss of the rotational and architectural torque that maintains cellular integrity. This document serves as a formal invitation to the global scientific community to validate these predictive models through clinical and experimental trials planned for the 2026-2028 cycle. It unifies the Minimal Mass/Maximum Action Axiom with cosmic and biological organizational structures, establishing a new sovereign framework for 21st-century science.