Demonstration of the protective effects of melatonin and naringenin against hepatic injury induced by bile duct ligation in male rats

Key Points

• Hepatic injury is significantly reduced in male rats treated with melatonin and naringenin.
• An observed decrease in biomarkers for oxidative stress indicates effective protection from liver damage.
• Experimental model utilized was bile duct ligation in male rats to simulate hepatic injury.
• Results suggest potential clinical applications for melatonin and naringenin in liver health and disease.