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达拉非尼加曲美替尼相比维莫非尼单药治疗,显著提高了此前未接受治疗的携带BRAF V600E或V600K突变的转移性黑色素瘤患者的整体生存率,且未增加总体毒性。(资金支持来自葛兰素史克;ClinicalTrials.gov编号,NCT01597908)
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Caroline Robert
Bogusława Karaszewska
Jacob Schachter
New England Journal of Medicine
Massachusetts General Hospital
Inserm
The University of Sydney
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Robert等人(Sun,)研究了这个问题。
www.synapsesocial.com/papers/69d6bfdbfca0359822aa8315 — DOI: https://doi.org/10.1056/nejmoa1412690
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