Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

Chapman et al. (Sun,) studied this question.

www.synapsesocial.com/papers/69d7370bf07a12db70b8a5b5 — DOI: https://doi.org/10.1056/nejmoa1103782

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1. Phase III Multicenter Randomized Trial of the Dartmouth Regimen Versus Dacarbazine in Patients With Metastatic Melanoma· 1999 · 761 citations
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5. BRIM-2: An open-label, multicenter phase II study of vemurafenib in previously treated patients with <i>BRAF</i> V600E mutation-positive metastatic melanoma.· 2011 · 132 citations