Mir‐301b‐3p Targets Alx4 to Suppress Cisplatin Sensitivity in Breast Cancer through DNA Damage

Key Points

• This research aims to investigate the role of miR-301b-3p in breast cancer and its impact on cisplatin sensitivity.
• Examined the effects of miR-301b-3p on breast cancer cell proliferation and cisplatin sensitivity
• Investigated the regulatory relationship between miR-301b-3p and ALX4
• Analyzed the involvement of DNA damage pathways in the mechanism of action.
• miR-301b-3p promotes breast cancer cell proliferation
• miR-301b-3p reduces sensitivity to cisplatin
• ALX4 suppression is linked to the observed changes in DNA damage response.